[CIS-PAGID] Adult with recurrent "Zoster"

Stan Ress Stan.Ress at uct.ac.za
Thu Dec 30 03:48:50 EST 2010


Talking about "Good old-fashioned DTH skin tests", does anyone know if
the multitest-CMI panel of 7 ags plus control, made by Pasteur Merieux,
is still available and where it can be obtained? We used them years ago,
but I can't source them now, and literature citing their use seems
largely to have dried up around 2004.

Thanks & Regards,

Stan


--
Stanley Ress
Associate Professor of Medicine
Head: Division of Clinical Immunology
Department of Medicine
H47 Old Main Building-room 26
Groote Schuur Hospital and UCT
Observatory 7925
Cape Town
South Africa
TEL:INTERN. + 2721-4066201 or 4066197
FAX: " + 2721-4486815
Cell: 0833115482
email: stan.ress at uct.ac.za

>>> "Berger, Melvin" <Melvin.Berger at UHhospitals.org> 2010/12/30 08:26

AM >>>
1. Good old-fashioned DTH skin tests. 2. T-cell response by Elispot to
autologous cells infected with VZV - see what cytokines he makes
compared to controls. 3. TLR responses. 4. Reminders to take his
prophylaxis.

Melvin Berger, M.D., Ph.D.
Adjunct Professor of Pediatrics and Pathology
Case Western Reserve University
Cleveland, OH 44106

________________________________

From: pagid-bounces at list.clinimmsoc.org on behalf of Church, Joseph
Sent: Wed 12/29/2010 7:09 PM
To: pagid at list.clinimmsoc.org
Subject: [CIS-PAGID] Adult with recurrent "Zoster"



Colleagues:



A 57yo man was referred for recurrent Herpes zoster. Lesions have
recurred ~ 2 times a year for 20 years. They affect the same facial
location (right ear). Outbreaks are associated with increased stress
and missing Valtrex prophylaxis. He has absolutely no other infectious
history and is otherwise healthy.



NORMAL laboratory findings include the following:

*CBC, CMP, sed rate, CRP
*IgG, IgA, IgM
*Antibody responses to tetanus, hepatitis A and Pneumovaxtm
*T, B and NK numbers
*PHA and PWM LPAs
*Tetanus, Candida and VZV LPAs
*NK cytotoxicity (Cincinnati Children's)
*CTL cytotoxicity (Cincinnati Children's)



Other than the possibility that these episodes are not VZV-related,
does anyone have any other ideas?



Joe Church

Children's Hospital Los Angeles






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