[CIS-PAGID] Adult with recurrent "Zoster"

[Church, Joseph]

Thanks, Mel.  

 

Has anyone had a similar case?  

 

Joe Church

 

________________________________

From: pagid-bounces at list.clinimmsoc.org
[mailto:pagid-bounces at list.clinimmsoc.org] On Behalf Of Berger, Melvin
Sent: Wednesday, December 29, 2010 10:27 PM
To: pagid at list.clinimmsoc.org
Subject: RE: [CIS-PAGID] Adult with recurrent "Zoster"

 

1. Good old-fashioned DTH skin tests.  2. T-cell response by Elispot to
autologous cells infected with VZV - see what cytokines he makes
compared to controls. 3. TLR responses. 4. Reminders to take his
prophylaxis. 

 

Melvin Berger, M.D., Ph.D.

Adjunct Professor of Pediatrics and Pathology

Case Western Reserve University

Cleveland, OH 44106

 

________________________________

From: pagid-bounces at list.clinimmsoc.org on behalf of Church, Joseph
Sent: Wed 12/29/2010 7:09 PM
To: pagid at list.clinimmsoc.org
Subject: [CIS-PAGID] Adult with recurrent "Zoster"

Colleagues:

 

A 57yo man was referred for recurrent Herpes zoster.   Lesions have
recurred ~ 2 times a year for 20 years.  They affect the same facial
location (right ear).  Outbreaks are associated with increased stress
and missing Valtrex prophylaxis.  He has absolutely no other infectious
history and is otherwise healthy.  

 

NORMAL laboratory findings include the following:

*	CBC, CMP, sed rate, CRP 
*	IgG, IgA, IgM 
*	Antibody responses to tetanus, hepatitis A and Pneumovaxtm 
*	T, B and NK numbers 
*	PHA and PWM LPAs 
*	Tetanus, Candida and VZV LPAs 
*	NK cytotoxicity (Cincinnati Children's) 
*	CTL cytotoxicity (Cincinnati Children's) 

 

Other than the possibility that these episodes are not VZV-related, does
anyone have any other ideas?

 

Joe Church

Children's Hospital Los Angeles

 

 


---------------------------------------------------------------------
CONFIDENTIALITY NOTICE: This e-mail message, including any attachments, 
is for the sole use of the intended recipient(s) and may contain
confidential
or legally privileged information. Any unauthorized review, use,
disclosure
or distribution is prohibited. If you are not the intended recipient,
please
contact the sender by reply e-mail and destroy all copies of this
original message. 
---------------------------------------------------------------------



---------------------------------------------------------------------
CONFIDENTIALITY NOTICE: This e-mail message, including any attachments, 
is for the sole use of the intended recipient(s) and may contain confidential
or legally privileged information. Any unauthorized review, use, disclosure
or distribution is prohibited. If you are not the intended recipient, please
contact the sender by reply e-mail and destroy all copies of this original message.  

---------------------------------------------------------------------

-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://seven.pairlist.net/mailman/private/pagid/attachments/20101230/9b94a63f/attachment.htm>