[CIS-PAGID] Ivasive pneumococcal disease.

[Neil Romberg]

Is there evidence of aspleenia? The presence of Howell-Jolly bodies or and abdominal ultrasound?


On Mar 16, 2011, at 1:48 PM, Church, Joseph wrote:


> Colleagues:

>  

> I have evaluated a 4yo boy who had pneumococcal pneumonia + empyema at 2.5yo.

>  

> His fraternal twin died at 6mo from pneumococcal meningitis.

>  

> Normal labs have included:

> -          CBCs

> -          IgG, A, M, E

> -          Tetanus, Hib, pneumococcal vaccine responses (including persistently +19/23 serotypes following Pneumovax)

> -          CH50

> -          AH50

> -          T, B numbers

> -          Mitogen and antigen LPAs

> -          HIV PCR

> -          Mannose binding lectin

> -          TLR function (measured at IBT Labs).

>  

> What am I missing?

>  

> Joe Church

> Clinical Immunology and Allergy

> Children’s Hospital Los Angeles

>  

>  

> 

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Neil D. Romberg, MD
Allergy and Clinical Immunology Fellow
Yale University School of Medicine/Yale New Haven Hospital

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