[CIS-PAGID] Ivasive pneumococcal disease.

[Turvey, Stuart]

I would consider repeating the TLR functional assay given the clear susceptibility to invasive pneumococcal disease.


Stuart Turvey MB BS DPhil
Associate Professor
Division of Infectious and Immunological Diseases
University of British Columbia
BC Children's Hospital and Child & Family Research Institute
950 West 28 Avenue
Vancouver BC V5Z 4H4
Ph: 604 875 2345 x5094
Fax: 604 875 2226
________________________________
From: pagid-bounces at list.clinimmsoc.org [pagid-bounces at list.clinimmsoc.org] On Behalf Of Church, Joseph [JChurch at chla.usc.edu]
Sent: March 16, 2011 10:48 AM
To: pagid at list.clinimmsoc.org
Subject: [CIS-PAGID] Ivasive pneumococcal disease.

Colleagues:

I have evaluated a 4yo boy who had pneumococcal pneumonia + empyema at 2.5yo.

His fraternal twin died at 6mo from pneumococcal meningitis.

Normal labs have included:
-          CBCs
-          IgG, A, M, E
-          Tetanus, Hib, pneumococcal vaccine responses (including persistently +19/23 serotypes following Pneumovax)
-          CH50
-          AH50
-          T, B numbers
-          Mitogen and antigen LPAs
-          HIV PCR
-          Mannose binding lectin
-          TLR function (measured at IBT Labs).

What am I missing?

Joe Church
Clinical Immunology and Allergy
Children’s Hospital Los Angeles



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