[CIS-PAGID] Duration of treatment for Crohn's in XLA

[Kate Sullivan]

I don't know the answer to your question and was surprised by the question.  I think of XLA as being more free from autoimmune disease than other immune deficiencies.  I wonder how common this is and wonder if this is perhaps a topic for some research investigation.

Kate
Kate Sullivan, MD PhD
Professor of Pediatrics
ARC 1216 Immunology CHOP
3615 Civic Center Blvd.
Philadelphia, PA 19104
(p) 215-590-1697
(f) 267-426-0363


On Apr 6, 2011, at 5:27 PM, Richard Wasserman wrote:


> I have cared for this 23yo with XLA (BTK mutation confirmed) who has a ten year history of Crohn's. He has been maintained on azathioprine and has never been exposed to a biologic response modifier. When azathioprine was weaned about five years ago there was relapse. He has been doing very well since his remission was reinduced with prednisone. He now asks about stopping azathioprine. He has never had any other autoimmune diathases. Is there any experience with discontinuing treatment in XLA patients with Crohn's?

> Thanks,

> Richard Wasserman

> Dallas

> 

> -- 

> Richard L. Wasserman, MD, PhD

> DallasAllergyImmunology

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