[CIS-PAGID] CVID Pt wheezes 12h after Hizentra

[Nacho Gonzalez]

Is there any possibility of pulmonary embolism?

Luis Ignacio Gonzalez-Granado
Immunodeficiencies. Hospital 12 octubre. Madrid. Spain.

2011/4/16 Saxon, Andy M.D. <ASaxon at mednet.ucla.edu>


>  What the heck are you doing taking care of 57 yo ladies down at

> Children's Joe?

>

> I have not seen it but Marc Riedl and others have far more experience with

> the SQ than I do. I'd get spirometry before her infusion and then again when

> see is wheezing to see what you got there objectively

>

> Andy Saxon

> UCLA

>

>  ------------------------------

> *From:* pagid-bounces at list.clinimmsoc.org [mailto:

> pagid-bounces at list.clinimmsoc.org] *On Behalf Of *Church, Joseph

> *Sent:* Friday, April 15, 2011 5:49 PM

> *To:* pagid at list.clinimmsoc.org

> *Subject:* [CIS-PAGID] CVID Pt wheezes 12h after Hizentra

>

>   Colleagues:

>

>

>

> I recently started to follow a 57yo lady with CVID.  She has lots of other

> complaints (fatigue, arthralgias, thyroid disease, migraines, mitral valve

> prolapse…).

>

>

>

> She had significant reactions following Vivaglobin: fatigue, nausea, hives.

>

>

>

> She is receiving Hizentra.  Approximately 12h after each infusion she

> complains of wheezing.  This is responsive to Xopenex and not of a severity

> to consider discontinuing the infusions.

>

>

>

> Has anyone seen this in patients following SCIG?

>

>

>

> IgG anti-IgA is pending.

>

>

>

> Thank you for your thoughts.

>

>

>

> Joe Church

>

> Children’s Hospital Los Angeles

>

>

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