[CIS-PAGID] question about TLR defects

[raas0027 at umn.edu]

Good morning all,

Two year-old with 20-month history of recurrent otitis media and 
bronchitis/pneumonia historically treated as an outpatient.

Basic immunologic evaluation unremarkable(cbc, Ig's, flow cytometry, 
complement, MBL, etc.)

I suspect GERD and emerging atopy significant contributing factors.

Currently ospitalized with pneumonia with pleural effusion.


This patient becomes febrile and CRP is quite elevated in the present case. 
FOR THIS REASON I DOUBT A TLR DEFECT is on the differential diagnosis.

Agree or disagree?



Thanks for your thoughts.

-Jason


-- 
Jason Raasch, MD

Midwest Immunology Clinic
15700 37th Ave N
Suite 110
Plymouth, MN 55446

(Phone) 763.577.0008
(FAX)   763.5770192