[CIS-PAGID] CVID + LIP

[Nelson, Robert P Jr]

Joe,
If it has some nodular characteristics, we have several times with good results. 375mg/m2 q week times 4 weeks.  Chest CT before and biopsied dominant lymph node if present.  If LDH is high, we have gotten tissue by mediastinoscopy, VATS or  bronch to rule out lymphoma beforehand.  Have coded it lymphoproliferative disease and gotten coverage.  We have premed scheme al la that which the lymphoma docs use and have order set for administration if you could use it.

Sincerely,

Bob 
________________________________________
From: pagid-bounces at list.clinimmsoc.org [pagid-bounces at list.clinimmsoc.org] on behalf of Church, Joseph [JChurch at chla.usc.edu]
Sent: Thursday, July 21, 2011 10:07 PM
To: pagid at list.clinimmsoc.org
Subject: [CIS-PAGID] CVID + LIP

Colleagues:

A 60yo female with long term CVID has had lymphoid interstitial pneumonitis that was biopsy documented in 2005.

She had developed worsening of symptoms over the past 6 months.

She is trying to avoid increasing her prednisone, currently at 10mg/d, because of coronary artery disease and hypertension; she could not tolerate CellCept.

Has anyone tried Rituximab in this setting?

Joe Church, MD
Children’s Hospital Los Angeles



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