[CIS-PAGID] AT patients with T-cell deficiency

[Church, Joseph]

Colleagues:

 

I follow a number of Ataxia Telangietasia patients, and several have low
T-cell numbers (e.g. CD4+ ~400), normal mitogen responses, but no
antigen-specific lymphoproliferative responses.  

 

Have any of you had AT patients who have developed opportunistic
infections such as Pneumocystis pneumonia, disseminated mycobacterial
disease, or disseminated CMV disease?

 

Joe Church

Children's Hospital Los Angeles



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