[CIS-PAGID] Lung transplantation in AD-HIES

[McComish, Jeremy S]

Dear team,

Does anyone have experience with lung transplantation in adult patients with AD-HIES? I have one such patient who is approaching the waitlist for lung transplant due to declining lung function on a background of bronchiectasis. She is currently stable on cotrimoxazole and itraconazole with a reasonable but inexorably declining lung function ie possibly a good window for transplantation. There are obvious concerns with the technical aspects (given her previous surgery) and post transplant immunosuppression.

Kind regards,

Jeremy

Dr Jeremy McComish FRACP FRCPA 
Clinical Immunologist and Immunopathologist
Acting Head of Unit
Department of Clinical Immunology and Allergy
Royal Melbourne Hospital