[CIS-PAGID] Hypogam following Fontan

[Church, Joseph]

Colleagues:

 

I am seeing a 7yo girl with hypoplastic left heart syndrome s/p Fontan
procedure.

 

As many of these patients she has developed progressively decreasing
IgG.  Her tetanus, Hib and pneumococcal antibodies remain protective,
and she has had no serious infections.  She also has T-lymphopenia.

 

Of particular interest is that her low IgG (currently 155 mg/dL) seems
out of proportion to her hypoalbuminemia (2.9-3.2 mg/dL).

 

Has anyone seen this combination of findings?

 

I am leaning toward beginning Ig replacement because of the progressive
decrease in IgG levels.  

 

Thanks for your help.

 

Joe Church

Children's Hospital Los Angeles

 

 

 

 



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