[CIS-PAGID] deficiency in terminal complement components

[Anete S Grumach]

I suggest to vaccinate the contactants (family members) for the same
agents. They are possible carriers.

Anete




Anete S Grumach, MD, PhD
Faculty of Medicine ABC, SP, Brazil
anete at grumach.com




2011/12/1 Saxon, Andy M.D. <ASaxon at mednet.ucla.edu>


> The antibiotics were Pen based but the last one we started was >10 years

> ago (boy time flies) and she no longer lives in this area. Pcn based

> antibiotics were  not perfect but that lady's brother had recurrent

> pneumococcal sepsis/meningitis (x2) and died and she was an asymptomatic

> adult who was sexually active. Clearly, if one were to do it "today" or be

> following such a subject, the decision would have to be based in current

> bacterial resistance and nature of patient and in consultation with ID.

>

> Andy Saxon

> UCLA

>

> -----Original Message-----

> From: pagid-bounces at list.clinimmsoc.org [mailto:

> pagid-bounces at list.clinimmsoc.org] On Behalf Of James N Moy

> Sent: Thursday, December 01, 2011 6:35 AM

> To: pagid at list.clinimmsoc.org

> Subject: Re: [CIS-PAGID] deficiency in terminal complement components

>

> Hi Andy,

> Which antibiotic do you use for prophylaxis in these patients?

> Jim Moy

> Rush University Medical Center

>

> -----Original Message-----

> From: pagid-bounces at list.clinimmsoc.org [mailto:

> pagid-bounces at list.clinimmsoc.org] On Behalf Of Saxon, Andy M.D.

> Sent: Thursday, December 01, 2011 8:32 AM

> To: 'pagid at list.clinimmsoc.org'

> Subject: Re: [CIS-PAGID] deficiency in terminal complement components

>

> We have always treated (the few adults we have seen) with vaccination and

> prophylaxis as their sepsis/meningitis can be so rapid as to be untreatable

> once they even get non-specific symptoms. Plus it puts an extra burden on

> the patient to know when to take the medicine rather than taking it daily.

>

> The patients who get recognized in new families are lucky to be alive...

>

> A. Saxon, MD

> UCLA

>

> -----Original Message-----

> From: pagid-bounces at list.clinimmsoc.org [mailto:

> pagid-bounces at list.clinimmsoc.org] On Behalf Of Philipp Henneke

> Sent: Thursday, December 01, 2011 3:09 AM

> To: pagid at list.clinimmsoc.org

> Subject: [CIS-PAGID] deficiency in terminal complement components

>

> We have recently diagnosed a patient with recurrent meningococcal

> meningitis to be deficient in terminal complement components.

> My question: What is the experience with antibiotic prophylaxis versus

> preemptive treatment when non specific symptoms of infection occur?

> Philipp Henneke

>

> Prof. Dr. med. Philipp Henneke

>

> UNIVERSITÄTSKLINIKUM FREIBURG

> Centrum für Chronische Immundefizienz (CCI) Zentrum für Kinder- und

> Jugendmedizin

>

> Tel Sekretariat 0761 270-77640

> Tel mobil 0162 285 2481

> Fax 0761 270 77600

> Breisacherstr. 117-2.OG, 79106 Freiburg

> philipp.henneke at uniklinik-freiburg.de

> http://www.cci.uniklinik-freiburg.de

>

>

>

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