[CIS-PAGID] WHIM BMT experience

[Michi]

No experience here and nit much elsewhere from the scant replies, but I can see why you consider SCT and would favor it too if you had a good donor.
Best regards,
Michael Albert

Am 12.04.2012 um 19:52 schrieb "Torgerson, Troy" <troy.torgerson at seattlechildrens.org>:


> I wanted to query the group about experience transplanting patients with WHIM syndrome as there is scant literature on the subject.  We have an unfortunate 3 y/o F recently diagnosed who was abused as an infant and has huge condolomas that have been excised on a few occasions.  She has been treated with topical imiquimod and we are considering intra-lesional cidofivir although this has not yet been done.  CD8 counts are about 50, she is intermittently neutropenic, but is not hypogamm at present.  At least 3 male relatives have died of “urologic”, penile, squamous cell carcinomas in their early 40’s – 50’s so we are concerned that her long-term prognosis is poor given the age at which she acquired HPV so we are considering transplant but would appreciate hearing of other experience.

>  

> Thanks,

> Troy

>  

> Troy R. Torgerson, MD PhD

>  

> Assistant Professor, Pediatric Immunology/Rheumatology

> University of Washington, Department of Pediatrics

>  

> Director, Immunology Diagnostic Laboratory

> Center for Immunity and Immunotherapies

> Seattle Children’s Research Institute

> 1900 9th Ave., C9S-7

> Seattle, WA  98101-1305

>  

> Tel:  (206) 987-7317

> Fax:  (206) 987-7310

>  

> Email:  Troy.Torgerson at seattlechildrens.org

>  

> 

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