[CIS-PAGID] Selective IgM deficiency

[Church, Joseph]

Colleagues:

I have just consulted on an woman with IgM deficiency (< 5 mg/dL) and selective antibody deficiency.

She has significant reactions to her Ig infusions, even SC.

Has anyone heard of IgG anti-IgM antibodies causing reactions to Ig infusions?

Is there any way to measure such antibodies?

Joe Church
Children's Hospital Los Angeles


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