[CIS PIDD] Chronic leukocytosis

[fabrício prado monteiro]

Think in DIRA (Def. IL 1 Receptor Antagonist)

F!

On 11 August 2012 15:24, Sorensen, Ricardo <RSoren at lsuhsc.edu> wrote:


>  Wilmer,****

>

> ** **

>

> As you point out in your differential, this could be a form of LAD. When

> did his cord fall off?****

>

> ** **

>

> I would Amos Etzioni for his opinion and advise directly:

> etzioni at rambam.health.gov.il****

>

> ** **

>

> Ricardo Sorensen****

>

> ** **

>

> *From:* pagid-bounces at list.clinimmsoc.org [mailto:

> pagid-bounces at list.clinimmsoc.org] *On Behalf Of *Wilmer Cordova Calderon

> *Sent:* Tuesday, August 07, 2012 2:46 AM

> *To:* pagid at list.clinimmsoc.org

> *Subject:* [CIS PIDD] Chronic leukocytosis****

>

> ** **

>

> Best regards, this a very difficult case because I dont have flow

> citometry and others advances test ****

>

> Here I sending all information that can have****

>

> Its a long time leukocytosis and hematology dont think in a malignancy (3

> year with it)****

>

> The patient is eutrophic, but with  recurrent and chronic infections****

>

> Ill thanks a lot your suggestions and comment****

>

> ** **

>

> ** **

>

> Age: 3 years****

>

> female****

>

> Date of birth: March 31, 2009****

>

> BACKGROUND****

>

> Product of 2nd pregnancy****

>

> Cesarean delivery, 8 months, birth weight 2900 g****

>

> Fall of umbilical cord at 10 days****

>

> Complete Vaccines: up years of age.****

>

> The 1st hospitalization: 15 days old FEVER OVER PNEUMONIA (WBC 70 000), is

> hospitalized for 1 month 15 days.****

>

> The 2nd hospitalization 1 year 2months, VIRAL BRONCHITIS (WBC 80 000),

> hospitalized for 1 month****

>

> infections****

>

> Cellulite: 5 times: internal angle left eye, left elbow, right thigh,

> vagina (2)****

>

> Otitis media: 4 times****

>

> Pneumonia: 1 time****

>

> Bronchitis 1 time****

>

> Sepsis: 2 times.****

>

> Apparently healthy relatives****

>

> Transfusion of red blood cells: once****

>

> Bone marrow aspirate 31/3/9, at the age of 1 year 11 months, without

> alteration, NO leukemia****

>

> Final control of CBC:****

>

> Leukocytes (55 000)****

>

> Eosinof (2%)****

>

> Segm (75%)****

>

> Lymphatic (18%)****

>

> Mon (4%)****

>

> Hb (7.7)****

>

> Retic (0.4%)****

>

> Serum iron (35)****

>

> Transfer (273)****

>

> % Sat transf (12.8%)****

>

> Protein electrophoresis 29/11/11: Hypoalbuminemia. Polyclonal increase of

> gamma globulin. Increased alpha 1 and 3.****

>

> DIAGNOSTICS:****

>

> Chronic leukocytosis:****

>

> Myeloproliferative syndrome. Leukocyte Adhesion Deficiency****

>

> Moderate chronic anemia - severe****

>

> Recurrent infection syndrome****

>

> Recurrent otitis media****

>

> Chronic otitis media left: fungal****

>

> recurrent cellulitis****

>

> chronic gingivostomatitis****

>

> Atopy: allergic rhinitis may****

>

> ** **

>

> HEMOGRAMA/FECHA****

>

>  ****

>

>  ****

>

>  ****

>

>  ****

>

> Recuento/Fecha****

>

> 28/01/2011****

>

> 15/02/2011****

>

> 24/02/11****

>

> 07/03/11****

>

> 14/03/11****

>

> 28/01/11****

>

> 01/06/11****

>

> 03/09/11****

>

> 02/11/11****

>

> 01/02/12****

>

> 21/02/12****

>

> 03/04/12****

>

> 12/06/12****

>

> 02/07/12****

>

> 30/07/12****

>

> Leucocitos n° absoluto/células/μL  ****

>

> 40200****

>

> 23100****

>

> 33800****

>

> 28500****

>

> 23400****

>

> 40 200****

>

> 23 960****

>

> 50 500****

>

> 30 280****

>

> 66 390****

>

> 33 100****

>

> 28 800****

>

> 43 460****

>

> 36 380****

>

> 55 000****

>

> Neutrófilos %/ células/μL****

>

> 26130****

>

> 14553****

>

> 24336****

>

> 20805****

>

> 13338****

>

> 26 532****

>

> 15 094,8****

>

> 32 825****

>

> 19 984,8****

>

> 53 775,9****

>

> 28 135****

>

> 19 296****

>

> 31 291,2****

>

> 27 285****

>

> 44 000****

>

> Linfocitos % células/μL****

>

> 12060****

>

> 6930****

>

> 6760****

>

> 6270****

>

> 7258****

>

> 12 060****

>

> 6 948,4****

>

> 13 635****

>

> 8 478,4****

>

> 6 639****

>

> 4 634****

>

> 7 776****

>

> 9 561,2****

>

> 6 548,4****

>

> 7 700****

>

> BASOFILOS****

>

> 402****

>

> 0****

>

> 0****

>

> 0****

>

> 234****

>

> 402****

>

> 0****

>

> 505****

>

> 0****

>

> 0****

>

> 0****

>

> 0****

>

> 0****

>

> 727,6****

>

> 0****

>

> Monocitos****

>

> 804****

>

> 1383****

>

> 1690****

>

> 1425****

>

> 2106****

>

> 804****

>

> 1 677,2****

>

> 2 020****

>

> 1 816,8****

>

> 4 647,3****

>

> 0****

>

> 1 152****

>

> 2 607,6****

>

> 1 819****

>

> 2 200****

>

> Eosinófilos****

>

> 402****

>

> 231****

>

> 1014****

>

> 0****

>

> 234****

>

> 402****

>

> 239,6****

>

> 1 515****

>

> 0****

>

> 1 327,8****

>

> 331****

>

> 576****

>

> 1 100****

>

> Hemoglobina.****

>

> 9.3****

>

> 9.1****

>

> 9.1****

>

> 8.6****

>

> 8.6****

>

> 9,30****

>

> 10,10****

>

> 10,40****

>

> 10,00****

>

> 9,00****

>

> 9,00****

>

> 10,10****

>

> 8,50****

>

> 7,30****

>

> 7,70****

>

> Hematocrito:****

>

> 30****

>

> 30****

>

> 30****

>

> 27****

>

> 27****

>

> 30****

>

> 32****

>

> 34****

>

> 32****

>

> 29****

>

> 29****

>

> 31****

>

> 27****

>

> 24****

>

> 25****

>

> Plaquetas:****

>

> 532****

>

> 450****

>

> 406****

>

> 427****

>

> 532 000****

>

> 300 000****

>

> 400 000****

>

> 374 000****

>

> 409 000****

>

> 250 000****

>

> 335 000****

>

> 502 000****

>

> 525 000****

>

> Elementos adicionales: RETICULOCITOS****

>

> 0.9****

>

> 2.7****

>

> 1.2****

>

> 0,9%****

>

> 0,7%****

>

> 1,4%****

>

> 0,7%****

>

> 0,8%****

>

> 1,9%****

>

> 1,5%****

>

> 1,1%****

>

> 1,90%****

>

> 0,4%****

>

> *COMENTARIO*****

>

> *ALGUNOS HEMATIES FRAGMENTADOS*****

>

> LINFO ATIPICO 1%****

>

> -- ****

>

> *Atte *****

>

> Wilmer Córdova****

>

> *Inmunología Alergología*****

>

> *Instituto Nacional** de Salud del **Niño - Perú*****

>

> http://www.isn.gob.pe****

>

> ** **

>




--
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://seven.pairlist.net/pipermail/pagid/attachments/20120813/1cd3f59e/attachment.html>