[CIS PIDD] Post-Fontan hypogam

[Sullivan, Kathleen]

Yes- it is extremely common.  We presume that the thoracic duct backs up and the total body T cell count is fine- but the peripheral blood levels are low.  That is pure speculation but we do have a study ongoing to better define the immune deficiency.

On Aug 21, 2012, at 9:29 PM, Church, Joseph wrote:


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> Colleagues:

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> I follow an 8yo boy with the following

>             - Protein losing enteropathy (history of)

>             - Fontan procedure for hypoplastic left heart

>             - IgG 334 IgA 50 IgM58

>             - CD3+ 26% (308), CD19 42% (478)

>             - Serum albumin 4.7 mg/dL.

>  

> Has any one seen this pattern of immunodeficiency in the face of a very normal serum albumin level?

>  

> Thank you for your thoughts.

>  

> Joe Church

> Children's Hospital Los Angeles

> 

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Kate Sullivan, MD PhD
Professor of Pediatrics
ARC 1216 Immunology CHOP
3615 Civic Center Blvd.
Philadelphia, PA 19104
(p) 215-590-1697
(f) 267-426-0363


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