[CIS PIDD] Primary immune deficiency and alpha-1 antitrypsin deficiency?

[Junker, Anne]

This goes way back in memory, but yes.  In fact, several with heterozygous AAT deficiency who had more severe lung and liver disease than non-AAT deficient immune deficient patients. Anne


Anne K. Junker, MD
Associate Professor and Associate Director, Faculty Affairs, Department of Pediatrics
Director, Clinical Immunology Service, BC Children's Hospital
Co-Chair, Canadian Child & Youth Health Coalition
Director, Maternal Infant Child Youth Research Network of Canada/Reseau de Recherche en Sante des Enfant et des Meres (MICYRN)
K4-223 4480 Oak Street
Vancouver, British Columbia
Canada  V6H 3V4
phone: 604-875-3591
fax: 604-875-2414
email: ajunker at cw.bc.ca



-----Original Message-----
From: pagid-bounces at list.clinimmsoc.org [mailto:pagid-bounces at list.clinimmsoc.org] On Behalf Of raas0027 at umn.edu
Sent: Thursday, September 06, 2012 10:16 AM
To: pagid at list.clinimmsoc.org
Subject: [CIS PIDD] Primary immune deficiency and alpha-1 antitrypsin deficiency?


Just a quick survey:

Anyone out there with patients who have both primary immune deficiency 
(e.g. CVID, CGD, etc.) that ALSO have alpha-1 antitrypsin deficiency?

PUBMED search revealed only a few cases reoports of HIV or IgG subclass 
deficiency.

Came up in conversation today and I could not remember ever hearing about a 
case.

Thanks for your thoughts.

-J

-- 
Jason Raasch, MD

Midwest Immunology Clinic
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