[CIS PIDD] [cis-pidd] Yellow fever vaccine

Mel.Berger at cslbehring.com Mel.Berger at cslbehring.com
Tue Dec 11 07:05:24 EST 2012


Mike- havng heard of a number of cases of "viscerottophic" disease from the yellow fever vaccine, I have been afraid to give it to CVID patients. I do not know whether virus is excreted. Also, one of the tyhpoid vaccines is live, so I suppose there is Gi shedding.

Mel



On Dec 10, 2012, at 9:26 PM, "Michael Blaese" <mblaese at comcast.net<mailto:mblaese at comcast.net>> wrote:

Dear colleagues,

IDF has received the following inquiry from a caregiver for a patient with CVID.

QUESTION: My daughter may be exposed to a person who is taking typhoid fever pills and a yellow fever shot for a trip to India. Is it necessary to avoid the person or how much contact with the person can be made safely?

Is there a risk of horizontal spread of yellow fever vaccine from a recently immunized individual to a patient with CVID? The CDC recommendation is to not allow recently vaccinated individuals to donate blood for 2 weeks, but I have not been able to find information on the potential risk of horizontal spread from ordinary contact. Does anyone have experience with the direct immunization of a CVID patient with the yellow fever vaccine causing significant problems for the patient?

Any information you can provide would be greatly appreciated. Maybe someone from a yellow fever endemic area might have direct experience with this question that just does not come up very often in the northern U.S.

Thanks

R Michael Blaese, MD
Immune Deficiency Foundation

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