[CIS PIDD] [cis-pidd] DiGeorge and live virus vaccines

Sullivan, Kathleen sullivak at mail.med.upenn.edu
Fri Aug 9 14:16:58 EDT 2013


There are two papers and one that is coming out soon.

Overall- if you use HIV guidelines-safety seems assured.

On Aug 9, 2013, at 2:07 PM, Verbsky, James wrote:


> Not sure we have any evidence for this…but we usually like to see a normal mitgens..then give varivax first since there is a treatment for any complications with this virus. Would be interested in what others do?

>

> Best

>

> James

>

>

> James W. Verbsky M.D./Ph.D.

> Associate Professor of Pediatrics and Microbiology

> Medical College of Wisconsin

> Milwaukee, WI

> 414-266-6701

>

>

>

> From: Haines, Kathleen M.D. [mailto:KHaines at HackensackUMC.org]

> Sent: Friday, August 09, 2013 1:01 PM

> To: CIS-PIDD

> Subject: [cis-pidd] DiGeorge and live virus vaccines

>

> I have a 2yo girl w/DiGeorge due/overdue for live virus vaccines. She is in good health. However her lymphocyte subsets are as follows: WBC 2500; CD3 707; CD4 483; CD8 217; CD 56/16 178. She has made good antibodies to tetanus and responded to 5/7 pneumococcal subtypes in Prevnar. Overall Igs: IgG 615 mg/dL; IgA 18 mg/dL; IgM 35 mg/dL. I haven’t done any lymphocyte functions.

>

> I’m usually happy to give the live vaccines when the CD8 is close to 300 without any functional tests. Should I go ahead and vaccinate w/ MMRV or hold off? Opinions?

>

> Kathleen A. Haines, MD

> Section Chief, Pediatric Immunology

> Section of Pediatric Rheumatology & Immunology

> Hackensack UMC

> 30 Prospect Ave.

> Hackensack, NJ 07601

>

> Tel: 551-996-5306

> Fax: 201-996-9815

> khaines at HackensackUMC.org

>

> <image001.png>

>

>

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Kate Sullivan, MD PhD
Professor of Pediatrics
ARC 1216 Immunology CHOP
3615 Civic Center Blvd.
Philadelphia, PA 19104
(p) 215-590-1697
(f) 267-426-0363



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