[CIS PIDD] [cis-pidd] Immunodeficiency post-Fontan procedure

[Boyce, Thomas G., M.D.]

Joe,

They can, especially due to the hypogam if it is low enough, but since the T cells they do have function normally they usually do not have problems from that aspect.  Unfortunately replacing the Ig doesn't work since they lose it too fast.  For the most part they do well.


Thomas G. Boyce, MD, MPH
Pediatric Infectious Diseases and Immunology
Mayo Clinic
Rochester, MN 55905
phone: 507-255-8464
fax: 507-255-7767


From: bounce-44116806-183824398 at lists.clinimmsoc.org [mailto:bounce-44116806-183824398 at lists.clinimmsoc.org] On Behalf Of Church, Joseph
Sent: Tuesday, November 12, 2013 3:23 PM
To: CIS-PIDD
Subject: [cis-pidd] Immunodeficiency post-Fontan procedure

Colleagues:

Protein losing enteropathy s/p Fontan procedure for hypoplastic left heart may result in severe hypogammaglobulinemia and T-lymphopenia.

Are these patients clinically immunocompromised?  i.e. do they experience opportunistic infections?

Joe Church
Children's Hospital Los Angeles



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