[CIS PIDD] [cis-pidd] "Safe" T-cell numbers for breast feeding?

[Church, Joseph]

Colleagues:

Newborn screening for SCID is identifying babies with  T-cells in the 300-500/mcL range.  This has raised the question:  what number would be "safe" to allow breast feeding by a CMV seropositive mom?

I have been asked this question about a 2 month old baby with CHARGE syndrome, a CD3+ count of 500 and CD4+ count of 335, and positive response to PHA.  The baby is clinically very stable except for tachypnea due to choanal atresia.

Joe Church
Children's Hospital Los Angeles






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