[CIS PIDD] [cis-pidd] "Safe" T-cell numbers for breast feeding?

[Boyce, Thomas G., M.D.]

Joe,

I don't think it should be an issue.  Baby should have plenty of CMV specific antibody.  Also, transmission is more efficient by saliva.  So if you are keeping her from breastfeeding baby need to keep her from kissing baby too!

Tom


Thomas G. Boyce, MD, MPH
Pediatric Infectious Diseases and Immunology
Mayo Clinic
Rochester, MN 55905
phone: 507-255-8464
fax: 507-255-7767


From: bounce-44195952-183824398 at lists.clinimmsoc.org [mailto:bounce-44195952-183824398 at lists.clinimmsoc.org] On Behalf Of Church, Joseph
Sent: Tuesday, December 03, 2013 9:58 AM
To: CIS-PIDD
Subject: [cis-pidd] "Safe" T-cell numbers for breast feeding?

Colleagues:

Newborn screening for SCID is identifying babies with  T-cells in the 300-500/mcL range.  This has raised the question:  what number would be "safe" to allow breast feeding by a CMV seropositive mom?

I have been asked this question about a 2 month old baby with CHARGE syndrome, a CD3+ count of 500 and CD4+ count of 335, and positive response to PHA.  The baby is clinically very stable except for tachypnea due to choanal atresia.

Joe Church
Children's Hospital Los Angeles





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