[CIS PIDD] [cis-pidd] H. pylori treatment regimens in CVID

[Nacho Gonzalez]

Dear Daniel,

when clarithromycin resistance is high (≥15 percent), quadruple therapy
should be used to treat H. pylori (In Spain resistance rates are over 35%
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953083/). So in our country I
would choose a 4-drug protocol. I think this is a country-specific decision

Regards,

Luis Ignacio Gonzalez-Granado
Immunodeficiencies. Pediatric Infectious Diseases.
Hematology & Oncology.
Hospital 12 octubre
Madrid. Spain




2014/1/7 Daniel E. Pleguezuelo <pleguezuelo at live.com>


> Dear all,

>

> We are following the 2011 Helen Chapel proposed surveillance program for

> early detection of Gastric Cancer in CVID patients (

> http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110315/) and have  patients

> positive for Urea Breath Test (UBT) without dyspeptic sympthoms. Does

> anyone have experience with treatment combinations for H. pylori

> eradication in CVID patients? Should we proceed with a short 7-day and

> 3-drug protocol, a 7-day but 4-drug protocol or an extended 14-day and

> 3-drug therapy?

>

> Thanks in advance,

>

> Daniel E. Pleguezuelo, MD

> Dept. of Clinical Immunology

> Hospital Universitario Ramón y Cajal

> Madrid, Spain.

>

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