[CIS PIDD] [cis-pidd] Lymphoma in XLA

[Klaus Warnatz]

Thanks Maria, 

we will try to collect these cases and would be very happy to include yours if you agree?

greetings to Athens

klaus
Prof. Dr. med. Klaus Warnatz

UNIVERSITÄTSKLINIKUM FREIBURG
University Medical Center Freiburg
Center for Chronic Immunodeficiency
Division of Rheumatology and Clinical Immunology

Tel: +49-761-270-77640 / FAX -71000 / Pager: 12-7100

Breisacher Str. 117, 79106 Freiburg, Germany
klaus.warnatz at uniklinik-freiburg.de
http://www.uniklinik-freiburg.de/cci

Am 05.05.2014 um 18:36 schrieb Maria G Kanariou:


> Dear all, 

> 

> We had a patient with XLA and T-cell lymphoma 15 years ago. 

> Unfortunately he passed away 6-8 months after the diagnosis. 

> 

> Maria 

> _______________________________

> Maria G. Kanariou, M.D.

> Director, Head of the Dept. of Immunology - Histocompatibility

> Specialized Center & Referral Center for Primary Immunodeficiencies - Paediatric Immunology

> "Aghia Sophia" Children's Hospital, 

> Thivon & Papadiamantopoulou str. 

> Athens 11527, Greece

> Emails: m.kanariou at gmail.com,

> http://www.paed-anosia.gr 

> 

> On 5 Μαϊ 2014, at 6:28 μ.μ., "Cunningham-Rundles, Charlotte" <charlotte.cunningham-rundles at mssm.edu> wrote:

> 

>> I have not ever seen this. 

>> 

>> 

>> Charlotte Cunningham-Rundles, MD, PhD

>> Departments of Medicine and Pediatrics

>> The David S Gottesman Professor

>> The Immunology Institute

>> Mount Sinai School of Medicine

>> 1425 Madison Avenue

>> New York, NY 10029

>> Phone: 212 659 9268

>> Fax: 212 987 5593

>> Email: Charlotte.Cunningham-Rundles at mssm.edu

>> 

>> 

>> From: warnatz <klaus.warnatz at uniklinik-freiburg.de>

>> Reply-To: "cis-pidd at lists.clinimmsoc.org" <cis-pidd at lists.clinimmsoc.org>

>> Date: Monday, May 5, 2014 7:16 AM

>> To: "cis-pidd at lists.clinimmsoc.org" <cis-pidd at lists.clinimmsoc.org>

>> Subject: Re: [cis-pidd] Lymphoma in XLA

>> 

>> Hi Kate, 

>> 

>> We are currently caring for a XLA patient with suspected T cell lymphoma. This is a cutaneous variant with splenomegaly (no histology available) and CD8 T cell expansion in the peripheral blood and fever and night sweats. We could not find a good alternative explanation of this oligoclonal CD8 expansion. 

>> What kind of lymphoma do you find?

>> 

>> Klaus

>> Prof. Dr. med. Klaus Warnatz

>> 

>> UNIVERSITÄTSKLINIKUM FREIBURG

>> University Medical Center Freiburg

>> Center for Chronic Immunodeficiency

>> Division of Rheumatology and Clinical Immunology

>> 

>> Tel: +49-761-270-77640 / FAX -71000 / Pager: 12-7100

>> 

>> Breisacher Str. 117, 79106 Freiburg, Germany

>> klaus.warnatz at uniklinik-freiburg.de

>> http://www.uniklinik-freiburg.de/cci

>> 

>> Am 05.05.2014 um 12:58 schrieb Sullivan, Kathleen:

>> 

>>> Has anyone seen lymphoma in an XLA patient?  I would think they would be at least somewhat protected.

>>> 

>>> 

>>> Kate

>>> Kate Sullivan, MD PhD

>>> Wallace Chair of Pediatrics

>>> Professor of Pediatrics

>>> ARC 1216 Immunology CHOP

>>> 3615 Civic Center Blvd.

>>> Philadelphia, PA 19104

>>> (p) 215-590-1697

>>> (f) 267-426-0363

>>> 

>>> 

>>> 

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>> 

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