[CIS PIDD] [cis-pidd] Protein losing enteropathy

[Heimall, Jennifer]

I follow a cohort of patients with PLE following Fontan with low IgG levels and lymphopenia. The vast majority are doing quite well without intervention. We have just monitored specific immunoglobulins and followed clinically. There are a few who did develop a change in infection history and for those we did start immunoglobulin replacement with subcutaneous replacement.
Jen

Sent from my iPhone

On Jul 23, 2014, at 6:28 PM, "Santhosh Kumar/FS/VCU" <skumar at vcu.edu<mailto:skumar at vcu.edu>> wrote:

Hello,
I would appreciate any input regarding this case. I tried to search the literature but  there is not much on this topic.
I am seeing a 4 y/o child in consultation with GI who has protein losing enteropathy which they are trying to figure out the cause. He has had an endoscopy and colonoscopy which are normal. His immunoglobulins are  trending down and most recent one is IgG 164, IgM 24, IgA 73. His lymphocyte enumeration is normal. His vaccine titers were low to start with but have responded well to vaccination challenge. He has no hx of recurrent infections. I was wondering if there is any reason to treat him with IVIG. The IgG level makes me little nervous but given his vaccine titers are protective i am willing to observe.

Thank you,

Santhosh Kumar, MD
Assistant Professor,
Training Program Director
Allergy & Immunology
Medical College of Virginia
Ph:804-628-1605
Fax-804-828-1751

---

The CIS-PIDD listserv is supported by:

[http://www.clinimmsoc.org/UserFiles/image/cis-pidd-list-logo_v1.jpg]
The science & practice of human immunology

P: +1.414.224.8095
E: info at clinimmsoc.org<mailto:info at clinimmsoc.org>

Not a member of CIS? Please visit www.clinimmsoc.org<https://cis.execinc.com/edibo/Signup> to join!

You are currently subscribed to cis-pidd as: heimallj at email.chop.edu<mailto:heimallj at email.chop.edu>.
To unsubscribe click here: http://lm.clinimmsoc.org/u?id=183824501.906e93a1a559050da00131563850ac9e&n=T&l=cis-pidd&o=45216716

---
The CIS-PIDD listserv is supported by the Clinical Immunology Society
The science & practice of human immunology

P: +1.414.224.8095
E: info at clinimmsoc.org

Not a member of CIS? Please visit www.clinimmsoc.org to join!

You are currently subscribed to cis-pidd as: pagid at list.clinimmsoc.org.
To unsubscribe click here: http://lm.clinimmsoc.org/u?id=183939985.3ea13d40a15475ac00ebbd9cd8a37d6d&n=T&l=cis-pidd&o=45217106
or send a blank email to leave-45217106-183939985.3ea13d40a15475ac00ebbd9cd8a37d6d at lists.clinimmsoc.org
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://seven.pairlist.net/pipermail/pagid/attachments/20140723/7f86892a/attachment-0001.html>