[CIS PIDD] [cis-pidd] therapeutic advise for severe Respiratory papillomatosis (RRP)

[Elie Haddad]

Dear Juan,
usually the immunological tests are normal in RRP, as they were in my patient.
All the best
Elie


Elie Haddad, MD, PhD,
Professor of Pediatrics, University of Montreal,
Head, Pediatric Immunology and Rheumatology Division,
CHU Sainte-Justine, 3175 Cote Sainte-Catherine
Montreal, QC, H3T 1C5, Canada
Ph: 1 514 345 4713
fax: 1 514 345 4897
e-mail: elie.haddad at umontreal.ca





Le 2014-09-26 à 14:17, Juan Carlos Aldave Becerra a écrit :

> Dear Dr. Haddad,
> I evaluated today a 7-yr-old boy with exactly the same problem (severe respiratory papillomatosis). Serum immunoglobulins and B-, T- and NK-cell counts are normal.
> Pneumologists will give him subcutaneous interferon alpha and nebulized cidofovir.
> My question is if I should look for immune defects. He has no problems with other micoorganisms appart from HPV.
> Best regards,
> Juan
> 
> Juan Carlos Aldave, MD
> Allergy and Clinical Immunology
> Lima, Perú
> 
> El 26/9/2014, a las 13:06, Elie Haddad <elie.haddad at umontreal.ca> escribió:
> 
>> Dear colleagues,
>> We have a 13 yo patient with severe respiratory papillomatosis.
>> Her lesions are progressing in the larynx and although a new surgery is scheduled, the ENT specialist is very worried and asked us for help.
>> I know that some years ago, someone posted the feasibility of IFNa in aerosol for these patients, but I cannot find the post.
>> Does anyone know how to do this (doses, frequency, solution) ?
>> Do you think it is a good idea ?
>> Do you think we should give systemic IFNa also (or only) ?
>> Any anti-viral drug that could help ?
>> Thanks
>> Elie
>> 
>> 
>> Elie Haddad, MD, PhD,
>> Professor of Pediatrics, University of Montreal,
>> Head, Pediatric Immunology and Rheumatology Division,
>> CHU Sainte-Justine, 3175 Cote Sainte-Catherine
>> Montreal, QC, H3T 1C5, Canada
>> Ph: 1 514 345 4713
>> fax: 1 514 345 4897
>> e-mail: elie.haddad at umontreal.ca
>> 
>> 
>> 
>> 
>> 
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