[CIS PIDD] [cis-pidd] Low TRECs, nromal mitogens, progressive lymphopenia

Daniel Conway dhconway at hotmail.com
Tue Jan 6 20:50:03 EST 2015


Any vaccine responses or Ig's?

Sincerely,
Daniel H. Conway, MD
Assistant Professor of Pediatrics
St. Christopher's Hospital for Children
Drexel University College of Medicine

> On Jan 6, 2015, at 8:47 PM, Richard Wasserman <drrichwasserman at gmail.com> wrote:
> 
> 
> Please give me your thoughts on the best next steps for this six month old male who is thriving and has never been infected.
> 
> July 3, 2014 - Date of Birth
> 
> July 4, 2014, July 11, 2014 - Very Low TRECs
> 
> July 25, 2014
> 
> Absolute Lymphocytes L 3428 (cells/uL) 3400-7600
> 
> Absolute Cd3+ Cells L 1845 (cells/uL) 2500-5500 
> 
> Absolute Cd4+ Cells L 1435 (cells/uL) 1600-4000 
> 
> Absolute Cd8+ Cells L 389 (cells/uL) 680-1700 
> 
> Absolute Nk Cells (cd16+cd56+cells) 735 (cells/uL) 170-1100 
> 
> Absolute Cd19+ Cells L 828 (cells/uL) 300-2000 
> 
> Absolute Cd3+Cd4+Cd45RA+Cd62L+ 1260 (cells/uL) 1200-3600
> 
> Absolute Cd3+Cd4+Cd45RO+ 232 (cells/uL) 60-900
> 
> Absolute Cd3+Cd8+Cd45RA+Cd62L+ 363 (cells/uL) 3800-1300
> 
> Absolute Cd3+Cd4+Cd45RO+ 18 (cells/uL) 30-330
> 
> PHA, PWM and ConA stimulation was normal
> 
> January 5, 2015
> 
> Absolute Lymphocytes L 1559 (cells/uL) 4000-13500
> 
> Absolute Cd3+ Cells L 754 (cells/uL) 2160-5540 
> 
> Absolute Cd4+ Cells L 547 (cells/uL) 1390-4080 
> 
> Absolute Cd8+ Cells L 222 (cells/uL) 600-1490 
> 
> Absolute Nk Cells (cd16+cd56+cells) 184 (cells/uL) 160-930 
> 
> Absolute Cd19+ Cells L 519 (cells/uL) 740-2560 
> 
>  Thanks,
> Richard
> -- 
> Richard L. Wasserman, MD, PhD
> DallasAllergyImmunology
> 7777 Forest Lane, Suite B-332
> Dallas, Texas 75230
> Office (972) 566-7788
> Fax (972) 566-8837
> Cell (214) 697-7211
> ---
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