[CIS PIDD] [cis-pidd] Low TRECs, nromal mitogens, progressive lymphopenia

[Daniel Conway]

I am interested in another downstream function of genes involved in recombination- like specific antibody formation. 

Sincerely,
Daniel H. Conway, MD
Assistant Professor of Pediatrics
St. Christopher's Hospital for Children
Drexel University College of Medicine

> On Jan 6, 2015, at 9:37 PM, Richard Wasserman <drrichwasserman at gmail.com> wrote:
> 
> IgM at three weeks of age was 46mg/dL
> 
>> On Tue, Jan 6, 2015 at 8:21 PM, Cooper, Megan <Cooper_M at kids.wustl.edu> wrote:
>> Hi Richard - it looks as if all the populations are dropping, I might consider ADA (somewhat delayed onset).
>> 
>> Megan
>> 
>>> Megan A. Cooper, MD, PhD
>>> Assistant Professor, Department of Pediatrics
>>> Division of Rheumatology
>>> Washington University School of Medicine
>>> Cooper_m at kids.wustl.edu
>>> Lab website: http://research.peds.wustl.edu/Default.aspx?alias=research.peds.wustl.edu/Labs/Cooper_M
>> 
>> 
>> On Jan 6, 2015, at 7:47 PM, Richard Wasserman <drrichwasserman at gmail.com> wrote:
>> 
>>> 
>>> Please give me your thoughts on the best next steps for this six month old male who is thriving and has never been infected.
>>> 
>>> July 3, 2014 - Date of Birth
>>> 
>>> July 4, 2014, July 11, 2014 - Very Low TRECs
>>> 
>>> July 25, 2014
>>> 
>>> Absolute Lymphocytes L 3428 (cells/uL) 3400-7600
>>> 
>>> Absolute Cd3+ Cells L 1845 (cells/uL) 2500-5500 
>>> 
>>> Absolute Cd4+ Cells L 1435 (cells/uL) 1600-4000 
>>> 
>>> Absolute Cd8+ Cells L 389 (cells/uL) 680-1700 
>>> 
>>> Absolute Nk Cells (cd16+cd56+cells) 735 (cells/uL) 170-1100 
>>> 
>>> Absolute Cd19+ Cells L 828 (cells/uL) 300-2000 
>>> 
>>> Absolute Cd3+Cd4+Cd45RA+Cd62L+ 1260 (cells/uL) 1200-3600
>>> 
>>> Absolute Cd3+Cd4+Cd45RO+ 232 (cells/uL) 60-900
>>> 
>>> Absolute Cd3+Cd8+Cd45RA+Cd62L+ 363 (cells/uL) 3800-1300
>>> 
>>> Absolute Cd3+Cd4+Cd45RO+ 18 (cells/uL) 30-330
>>> 
>>> PHA, PWM and ConA stimulation was normal
>>> 
>>> January 5, 2015
>>> 
>>> Absolute Lymphocytes L 1559 (cells/uL) 4000-13500
>>> 
>>> Absolute Cd3+ Cells L 754 (cells/uL) 2160-5540 
>>> 
>>> Absolute Cd4+ Cells L 547 (cells/uL) 1390-4080 
>>> 
>>> Absolute Cd8+ Cells L 222 (cells/uL) 600-1490 
>>> 
>>> Absolute Nk Cells (cd16+cd56+cells) 184 (cells/uL) 160-930 
>>> 
>>> Absolute Cd19+ Cells L 519 (cells/uL) 740-2560 
>>> 
>>>  Thanks,
>>> Richard
>>> -- 
>>> Richard L. Wasserman, MD, PhD
>>> DallasAllergyImmunology
>>> 7777 Forest Lane, Suite B-332
>>> Dallas, Texas 75230
>>> Office (972) 566-7788
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>> 
>> 
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> 
> 
> 
> -- 
> Richard L. Wasserman, MD, PhD
> DallasAllergyImmunology
> 7777 Forest Lane, Suite B-332
> Dallas, Texas 75230
> Office (972) 566-7788
> Fax (972) 566-8837
> Cell (214) 697-7211
> ---
> 
> The CIS-PIDD listserv is supported by:
> 
> 
> The science & practice of human immunology
> 
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> E: info at clinimmsoc.org
> 
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