[CIS PIDD] [cis-pidd] Low TRECs, nromal mitogens, progressive lymphopenia

[Richard Wasserman]

IgM at three weeks of age was 46mg/dL

On Tue, Jan 6, 2015 at 8:21 PM, Cooper, Megan <Cooper_M at kids.wustl.edu>
wrote:

>   Hi Richard - it looks as if all the populations are dropping, I might
> consider ADA (somewhat delayed onset).
>
>  Megan
>
>   Megan A. Cooper, MD, PhD
>
> Assistant Professor, Department of Pediatrics
>
> Division of Rheumatology
>
> Washington University School of Medicine
>
> Cooper_m at kids.wustl.edu
>
> Lab website:
> http://research.peds.wustl.edu/Default.aspx?alias=research.peds.wustl.edu/Labs/Cooper_M
>
>
> On Jan 6, 2015, at 7:47 PM, Richard Wasserman <drrichwasserman at gmail.com>
> wrote:
>
>
>  Please give me your thoughts on the best next steps for this six month
> old male who is thriving and has never been infected.
>
>  *July 3, 2014 - Date of Birth*
>
>  *July 4, 2014, **July 11, 2014 - Very Low TRECs*
>
> * July 25, 2014*
>
>  Absolute Lymphocytes L 3428 (cells/uL) 3400-7600
>
>  Absolute Cd3+ Cells L 1845 (cells/uL) 2500-5500
>
>  Absolute Cd4+ Cells L 1435 (cells/uL) 1600-4000
>
>  Absolute Cd8+ Cells L 389 (cells/uL) 680-1700
>
>  Absolute Nk Cells (cd16+cd56+cells) 735 (cells/uL) 170-1100
>
>  Absolute Cd19+ Cells L 828 (cells/uL) 300-2000
>
>  Absolute Cd3+Cd4+Cd45RA+Cd62L+ 1260 (cells/uL) 1200-3600
>
>  Absolute Cd3+Cd4+Cd45RO+ 232 (cells/uL) 60-900
>
>  Absolute Cd3+Cd8+Cd45RA+Cd62L+ 363 (cells/uL) 3800-1300
>
>  Absolute Cd3+Cd4+Cd45RO+ 18 (cells/uL) 30-330
>
>  PHA, PWM and ConA stimulation was normal
>
>  *January 5, 2015*
>
>  Absolute Lymphocytes L 1559 (cells/uL) 4000-13500
>
>  Absolute Cd3+ Cells L 754 (cells/uL) 2160-5540
>
>  Absolute Cd4+ Cells L 547 (cells/uL) 1390-4080
>
>  Absolute Cd8+ Cells L 222 (cells/uL) 600-1490
>
>  Absolute Nk Cells (cd16+cd56+cells) 184 (cells/uL) 160-930
>
>  Absolute Cd19+ Cells L 519 (cells/uL) 740-2560
>
>   Thanks,
>  Richard
> --
> Richard L. Wasserman, MD, PhD
> DallasAllergyImmunology
> 7777 Forest Lane, Suite B-332
> Dallas, Texas 75230
> Office (972) 566-7788
> Fax (972) 566-8837
> Cell (214) 697-7211
>
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-- 
Richard L. Wasserman, MD, PhD
DallasAllergyImmunology
7777 Forest Lane, Suite B-332
Dallas, Texas 75230
Office (972) 566-7788
Fax (972) 566-8837
Cell (214) 697-7211

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