[CIS PIDD] [cis-pidd] recurrent Enterovirus meningitis

Church, Joseph JChurch at chla.usc.edu
Wed Apr 22 15:06:07 EDT 2015


At 11 years of age the patient likely received Prevnar7.  Did you boost with Pneumovax?  And how many S. pneumoniae serotypes were in your follow-up antibody analysis?

Joe Church
Children's Hospital Los Angeles

From: Leiding, Jennifer [mailto:jleiding at health.usf.edu]
Sent: Wednesday, April 22, 2015 8:50 AM
To: CIS-PIDD
Subject: [cis-pidd] recurrent Enterovirus meningitis

Hi all:

We are following an 11yo little girl who has had enterovirus meningitis twice with symptoms of headache, photophobia, nausea and emesis. The first episode was at age 9 and once last year. She also had 2 episodes of similar symptoms at age 3 and 6 but a lumbar puncture was never performed. She is growing well and is developmentally normal. Other infections have included pneumonia that was CXR documented 2 times treated with oral antibiotics and several episodes of otitis media. Her immune evaluation has included normal immunoglobulins, normal vaccine responses to diptheria, tetanus, and pneumococcus, and normal CH50, NK cell functional analysis, and lymphocyte subset analysis. T cell proliferative studies normal other than low response to Candida.

MRI of the spine was performed in the last year due to low back pain and was normal.


Any ideas about further evaluation?

Thanks,
Jennifer Leiding



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