[CIS PIDD] [cis-pidd] live vaccines in Digeorge population

[Anastasiya Ashurova]

Hi

We are following a 15 month old DiGeorge baby found to have a 22q11
deletion at birth.  We are in the process of clearing her for the MMR
vaccine.  Workup has shown normal T/B/NK flow cytometry, protective titers
to Tetanus (1.86), Hib (2.39) with 13 of 13 protective pneumococcal titers.
She had a normal proliferative response to PHA, PW, and Con A but did not
proliferate to tetanus and although she had a response to candida, it was
not robust.   Would you vaccinate this patient with a live vaccines?



Thank you,

Anastasiya Kleva

Fellow, Division of Allergy and Immunology

Cohen’s Children’s Medical Center

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