[CIS PIDD] [cis-pidd] live vaccines in Digeorge population

[Verbsky, James]

Yes

Sent from my iPhone

On Apr 23, 2015, at 2:58 PM, "Anastasiya Ashurova" <ana.ashurova at gmail.com<mailto:ana.ashurova at gmail.com>> wrote:

Hi
We are following a 15 month old DiGeorge baby found to have a 22q11 deletion at birth.  We are in the process of clearing her for the MMR vaccine.  Workup has shown normal T/B/NK flow cytometry, protective titers to Tetanus (1.86), Hib (2.39) with 13 of 13 protective pneumococcal titers.  She had a normal proliferative response to PHA, PW, and Con A but did not proliferate to tetanus and although she had a response to candida, it was not robust.   Would you vaccinate this patient with a live vaccines?

Thank you,
Anastasiya Kleva
Fellow, Division of Allergy and Immunology
Cohen’s Children’s Medical Center

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