[CIS PIDD] [cis-pidd] CVID and diarrhoea
Joshi, Avni Y., M.D.
Joshi.Avni at mayo.edu
Thu May 21 11:58:27 EDT 2015
Dear Panida and Carla,
If you missed this article on norovirus in CVID and the role of ribavirin:
http://www.nature.com/ajg/journal/v110/n2/full/ajg2014432a.html
Thanks,
Avni
Avni Joshi
Mayo Clinic
From: Sriaroon, Panida [mailto:psriaroo at health.usf.edu]
Sent: Thursday, May 21, 2015 10:24 AM
To: CIS-PIDD
Subject: Re:[cis-pidd] CVID and diarrhoea
Hi Carla,
We have a teenager with CVID and leukopenia, who has suffered from chronic norovirus enteritis which causes diarrhea and weight loss. Did you look for norovirus in your patient? Our patient did not respond to oral IgG therapy, and he is still shedding the virus.
Panida
Panida Sriaroon, MD
Associate Professor
Associate Director, Fellowship Program
Associate Director, USF/All Children's Hospital Allergy/Immunology clinic
Beeper 727.825.4379
Office 727.553.3521
E-mail:psriaroo at health.usf.edu
________________________________
From: Neumann, Carla Dr.med. <Carla.Neumann at med.uni-muenchen.de<mailto:Carla.Neumann at med.uni-muenchen.de>>
Sent: Thursday, May 21, 2015 10:34 AM
To: CIS-PIDD
Subject: [cis-pidd] CVID and diarrhoea
Dear Colleagues,
I treat a 46 year old patient with CVID (with autoimmune manifestations in the past with sarcoid like granuloma, splenomegaly and lymphadenopathy, recurrent pancytopenia and erosive rheumatoid arthritis). The patient is currently suffering from newly onset leucopenia (800/µl) of unknown origin (to us) and from intractable diarrhoea for several months (no infectious cause, no inflammatory bowel disease in colonoscopy, gluten free diet because it was beneficial to her in the past). The rheumatoid arthritis was treated with rituximab more than 1 year ago and prednisolone 5mg/day.
I would appreciate your help concerning the questions:
- Ideas for treating the diarrhoea (patient is cachectic due to the massive diarrhoea)
- Ideas concerning the cause of leucopenia (could the cachexia be the cause?)
Thank you !
Yours
Carla Neumann
Outpatient clinic for adult immunodeficiency, Munich, Germany
__________________________________
Dr. med. Dr. med. univ. Carla Neumann
Internistin/Rheumatologin
AIDA - adulte Immundefektambulanz
Rheumaeinheit
Med. Klinik und Poliklinik IV
Klinikum der Universität München
Pettenkoferstrasse 8a
80336 München
Tel: 089/44005-3568
Fax: 089/44005-3719
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