[CIS PIDD] [cis-pidd] T cell lymphopenia/cryptococcal meningitis

[CIS-PIDD]

Posting on behalf of Larry Borish <lb4m at virginia.edu>:

52 previously completely healthy M.  Presents to hospital with cryptococcus meningitis.  CD4’s are 0.  No big surprise there.  But CD8s are also 0.  CD3s are 0.  CD19/CD20 and IG’s all normal.  NKs slightly low.  Chest CT is not remarkable.  No thymoma and no lymphadenopathy.  His bone marrow normal, except for absence of CD3, CD4, and CD8 cells.  But nothing to suggest lymphoma.  

I suspect autoimmune but can’t get my laboratory to do indirect IF.  Does anyone have any other ideas or know of a lab who can screen for autoantibodies?

Larry Borish, M.D.
Professor of Medicine
Asthma and Allergic Disease Center
University of Virginia
Charlottesville, VA 22908
(434) 243-6570
lb4m at virginia.edu

---
You are currently subscribed to cis-pidd as: pagid at list.clinimmsoc.org.
To unsubscribe click here: http://cts.dundee.net/u?id=96396833.5a9591ccd1e327fe6bc4d1543298c482&n=T&l=cis-pidd&o=3183928
or send a blank email to leave-3183928-96396833.5a9591ccd1e327fe6bc4d1543298c482 at lyris.dundee.net