[CIS PIDD] [cis-pidd] LAD1 and pregnancy

[CIS-PIDD]

Megan
I believe she has the moderate type of LAD I with more than 5% CD18 expressiion. Although pregnancy in LAD I patient is rare' I do not think special care should be taken. Did she had any wound healing problems if so delivery should be done without episiotomy if possible
Amos Etzioni
________________________________
From: CIS-PIDD [cis-pidd at lists.clinimmsoc.org]
Sent: Tuesday, April 19, 2016 12:11 AM
To: CIS-PIDD
Subject: [cis-pidd] LAD1 and pregnancy

Hi everyone,

We have a teenage patient with LAD1 (CD18) who was diagnosed at a late age and has primarily manifest as pyoderma gangrenosum and gingival infections.  She transferred care to us a few years ago doing relatively well on monthly IVIG after a number of different therapies, and for several reasons transplant wasn’t considered a good option.  She is now pregnant.  I was wondering if anyone had experience with LAD during pregnancy and anything that we should pass on to the OBs.

Thanks,

Megan


Megan A. Cooper, MD, PhD
Assistant Professor, Department of Pediatrics
Division of Rheumatology
Washington University School of Medicine
Cooper_m at kids.wustl.edu<mailto:Cooper_m at kids.wustl.edu>
Lab website: http://research.peds.wustl.edu/Default.aspx?alias=research.peds.wustl.edu/Labs/Cooper_M
(lab office) 314-286-0262
(lab fax) 314-286-2895




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