[CIS PIDD] [cis-pidd] SCID genetic diagnosis?

[CIS-PIDD]

I have a quick question about CGD carriers

I have a mother of a son with X-linked CGD who has had horrible oral mucositis as well as discoid lupus on her arms.  I know this can occur in carriers.  She dealt with this her entire life.  No other infections.

She has been tried on plaquenil, Imuran, topical steroids, and oral steroids (as a teenager, stopped since she didn't like the side effects)

Anyone care for moms of CGD patients with similar symptoms and if so has anything worked?

We are going to try a short course of steroids, and then perhaps colchicine.  Our next thought was TNF blockers (a little nervous with her SLE like rashes that things could worsen but if nothing else works we may try this.)

Thanks

James


James W. Verbsky M.D./Ph.D.
Associate Professor of Pediatrics and Microbiology
Medical Director, Clinical Immunology Research Laboratory
Medical Director, Clinical and Translational Research
Medical College of Wisconsin
Milwaukee, WI 



---
You are currently subscribed to cis-pidd as: pagid at list.clinimmsoc.org.
To unsubscribe click here: http://cts.dundee.net/u?id=96396833.5a9591ccd1e327fe6bc4d1543298c482&n=T&l=cis-pidd&o=3805431
or send a blank email to leave-3805431-96396833.5a9591ccd1e327fe6bc4d1543298c482 at lyris.dundee.net