[CIS PIDD] [cis-pidd] Vaccine associated?

Tue Oct 25 16:06:58 EDT 2016

Never after vaccine but several times in toddlers after viral, often mild, infection. 

Pere Soler Palacín, MD, PhD, MSc. 
Pediatric Infectious Diseases and Immunodeficiencies Unit. Hospital Universitari Vall d'He bron. 
Vall d'Hebron Research Institute (VHIR) 
Assistant Professor. Universitat Autònoma de Barcelona (UAB) 
Director of the Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies (Barcelona) 
Pg. de la Vall d'Hebron, 119-129 
08035 Barcelona. Spain. 
Tel. 0034934893140 / Fax 0034934893039 

psoler at vhebron.net / 34660psp at comb.cat 
Web: www.upiip.com 
My ORCID 
ResearchGate: http://www.researchgate.net/profile/Pere_Soler-Palacin 
Linked In : http://es.linkedin.com/pub/pere-soler-palac%C3%ADn/73/918/b16 
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----- Missatge original -----

De: "CIS-PIDD" <cis-pidd at lists.clinimmsoc.org> 
Per: "CIS-PIDD" <cis-pidd at lyris.dundee.net> 
Enviats: Dimarts, 25 de Octubre 2016 22:02:29 
Assumpte: [cis-pidd] Vaccine associated? 

Dear Colleagues, 

I recently saw a 6 month old female, born via C-section due to prolonged labor. In hospital for 5 days (due to mom recovery). Received Hepatitis B vaccine in hospital. She did have "baby acne" but no other rash or eczema recalled. Received normal 2 month vaccines with no concerns. Child was doing well and received 4 month vaccines. The next day, around 11-12 child was "acting different", mom also noted some frontal head / fontanelle swelling. Was spitting up more than usual (has a history of reflux) and had a mild fever < 100. Did go to ER (nl CT, nl U/A, LP performed) and fontanelle reduced. Only in hospital for one night, did go on antibiotics. No rash, fever or other symptoms noted. All other work up was negative. Mom noted persistent full fontanelle for about 10 days that resolved. Child is now fine and otherwise healthy in all respects. Her pediatrician did extensive research (also did contact CDC no other noted problems with other children and vaccines). R 
ecommendation at that time was for no DTaP or only DT at 6 month vaccine schedule. 

Has anyone had a child have this happen after vaccination? 

The recommendation was to give further vaccines separately going forward. Any concern specifically with one of the vaccines, particularly acellular pertussis? 

Thank you for any suggestions you may have, 

Sincerely, 

John 

John B. Meiser, M.D. 
Board Certified Allergy and Immunology 
Allergy and Asthma Center of Texas 
6946 Lebanon Rd. 
Frisco, TX 75034 
www.aactmd.com 
office: 972-377-9987 
fax: 972-377-9906 

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