[CIS PIDD] [cis-pidd] Experiences in using inactivated typhoid vaccine

[CIS-PIDD]

We offer clinical testing of the S. Typhi response.  We need pre and post serum.  Instructions are on the MCW website (http://www.mcw.edu/AllergyAsthmaImmunology/PatientCare/CIRL.htm) or you can call the lab directly (414-456-4165)

We have done many CVID patients and patients on IG replacement and it has been very useful in predicting defects in antibody production.  We have done some children...they also seem to respond but I don't think we have enough at this point to publish or demonstrate any age dependent affects.

Best

James

James Verbsky MD/PhD
Associate Professor of Pediatrics
Division of Rheumatology
Medical Director of CIRL
Medical Director Clinical and Translational Research
Medical College of Wisconsin


From: CIS-PIDD <cis-pidd at lists.clinimmsoc.org<mailto:cis-pidd at lists.clinimmsoc.org>>
Reply-To: CIS-PIDD <cis-pidd at lyris.dundee.net<mailto:cis-pidd at lyris.dundee.net>>
Date: Wednesday, December 7, 2016 at 1:11 PM
To: CIS-PIDD <cis-pidd at lyris.dundee.net<mailto:cis-pidd at lyris.dundee.net>>
Subject: [cis-pidd] Experiences in using inactivated typhoid vaccine

Hi everyone,

I know that there was discussion of this at CIS last year, but I was curious about everyone's experience in using inactivated typhoid vaccine for testing polysaccharide responses.  Has anyone accrued data on responses in pediatric patients?   Where are people sending the titers?

It would be wonderful to retire pneumovax for diagnostic use...

Thanks so much!
Mike


Michael D. Keller, MD

Assistant Professor, Division of Allergy / Immunology

Center for Cancer and Immunology Research

Jeffrey Modell Diagnostic and Research Center for

Primary Immunodeficiency Disorders

Children's National Health System

111 Michigan Ave NW, M7745A

Washington, DC 20010

Clinic: 202.476.3016

Office: 202.476.5843

Fax: 202.476.2280

www.ChildrensNational.org


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