[CIS PIDD] [cis-pidd] B-cell subsets

[CIS-PIDD]

Hi Joe,

Do your patients have only infections or also other
non-infectious manifestations of CVID?

Best,
Milica Mitrevski 

Il
02.02.2017 01:07 CIS-PIDD ha scritto: 

> Yes, very normal numbers. JC

> 
> FROM: CIS-PIDD [mailto:cis-pidd at lists.clinimmsoc.org] 
> SENT:
Wednesday, February 01, 2017 3:51 PM
> TO: CIS-PIDD
> SUBJECT: Re:
[cis-pidd] B-cell subsets 
> 
> Hi Joe, 
> 
> Do the patients have
normal numbers of B cells? 
> 
> Best, 
> 
> Jordan 
> 
> FROM: CIS-PIDD

> REPLY-TO: CIS-PIDD 
> DATE: Wednesday, February 1, 2017 at 2:34 PM
>
TO: CIS-PIDD 
> SUBJECT: [cis-pidd] B-cell subsets 
> 
> Colleagues:
>

> Several of my CVID patients have displayed phenotypes similar to the
following: 
> 
> · CD19+ IgD+ CD27- (naïve) 20% 
> 
> · CD19+ IgD+ CD27+
(memory) 48% 
> 
> · CD19+ IgD- CD27+ (switched memory 31% 
> 
> Are
there specific "CVID" genotypes that are likely to present with this
pattern? 
> 
> Joe Church 
> 
> Children's Hospital Los Angeles 
> 
>
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--

Milica Mitrevski, MD, PhD Clinical Immunology and Allergy
Specialist Sapienza University of Rome Department of Clinical Medicine
Viale dell'Università 37, 00185 Rome, Italy tel: +39 06 49972036 +39 349
5622376 mail: mitmilica at tiscali.it   


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