[CIS PIDD] [cis-pidd] IVIG or SCIG

[CIS-PIDD]

Joe,
I don't have experience with tamoxifen and IG but, as you know, the IVIG
thrombosis risk is related to factor 11a which is now low to absent from
most/all products. You can reduce the risk by treating every two weeks so
that the dose is low and with a long infusion time. I would still prefer
IGSC or IGHy.
Richard Wasserman
Dallas

On Tue, Jun 6, 2017 at 10:53 AM, CIS-PIDD <cis-pidd at lists.clinimmsoc.org>
wrote:

> Colleagues:
>
>
>
> I consulted on a 46yo F who requires immunoglobulin replacement therapy.
> She is s/p bilateral mastectomy for breast cancer and on tamoxifen as
> maintenance.
>
>
>
> Tamoxifen “slightly” increases the risk for DVTs etc.
>
>
>
> However, the patient would prefer IVIG over SCIG.
>
>
>
> Does anyone have experience with the combination of IVIG + tamoxifen and
> the risk of thrombotic events?
>
>
>
> Thank you for your help.
>
>
>
> Joe Church
>
> Children’s Hospital Los Angeles
>
>
>
>
>
>
>
> .
>
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-- 
Richard L. Wasserman, MD, PhD
Allergy Partners of North Texas
7777 Forest Lane, Suite B-332
Dallas, Texas 75230
Office (972) 566-7788
Fax (972) 566-8837
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