[CIS PIDD] [cis-pidd] VS: IVIG or SCIG

[CIS-PIDD]

Out of I think 3 such CVID patients I have seen, 1 had recurrent thrombosis, but that was before present day preparations and she had multiple (!) other risk factors.

If she refuses SCIG (which I would prefer) would then use IVIG.

Mikko



Mikko Seppänen
Director, Adjunct Professor, MD, PhD
Hospital District of Helsinki and Uusimaa, Children's Hospital, Rare Disease Center
P.O.Box 280, 00029 HUS |Lastenlinnantie 2, Helsinki
Senior Consultant
Hospital District of Helsinki and Uusimaa, Inflammation Center, Adult Primary Immunodeficiency Outpatient Clinic
mikko.seppanen at hus.fi<mailto:mikko.seppanen at hus.fi>
+358 9 47180201| +358 50 4279606
faxi +358 9 47174703
www.hus.fi<http://www.hus.fi/>; www.harvinaissairaudet.fi<http://www.harvinaissairaudet.fi/>

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Lähettäjä: cis-pidd at lyris.dundee.net [mailto:cis-pidd at lyris.dundee.net] Puolesta CIS-PIDD
Lähetetty: 6. kesäkuuta 2017 18:53
Vastaanottaja: CIS-PIDD <cis-pidd at lyris.dundee.net>
Aihe: [cis-pidd] IVIG or SCIG

Colleagues:

I consulted on a 46yo F who requires immunoglobulin replacement therapy.  She is s/p bilateral mastectomy for breast cancer and on tamoxifen as maintenance.

Tamoxifen "slightly" increases the risk for DVTs etc.

However, the patient would prefer IVIG over SCIG.

Does anyone have experience with the combination of IVIG + tamoxifen and the risk of thrombotic events?

Thank you for your help.

Joe Church
Children's Hospital Los Angeles



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