[PAGID] IVIG and aseptic meningitis

Amos Etzioni etzioni at rambam.health.gov.il
Wed Dec 5 10:26:31 EST 2007


Dear Cris
I have several patients with similar symptoms who respond very favorable
to a NSAID an hour before the infusion and 12 hours post.

Amos Etzioni MD
Professor of Pediatrics and Immunology
Director - Meyer Children's Hospital
Bat- Galim, Haifa, Israel 31096
Tel- 972-4-854 2936
Fax- 972-4-854 1870
Email - etzioni at rambam.health.gov.il

-----Original Message-----
From: pagid-bounces at list.clinimmsoc.org
[mailto:pagid-bounces at list.clinimmsoc.org] On Behalf Of Chris Seroogy
Sent: Wednesday, December 05, 2007 5:21 PM
To: pagid at list.clinimmsoc.org
Subject: [PAGID] IVIG and aseptic meningitis

Dear Colleagues,

I have a question about management of aseptic meningitis and IVIG.

We have a 5 y/o with chemotherapy-induced immunodeficiency who meets
criteria for immunoglobulin replacement. He just had his first infusion
(400mg/kg gammagard S/D) which went well, but 48 hours later developed
severe headache and stiff neck. I did not evaluate him, but the
heme/onc
colleagues felt he had aseptic meningitis and this resolved with pain
management.

My question is what has worked for individuals to prevent/prophylaxis
this
side effect? He needs the product and I am told subcutaneous is not an
option since he will pull out the tubing and it would be too much of a
time
commitment for the family. Thank you for any input! Regards, Chris




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