[PAGID] Attached umbilical cord in 8 week old

[Kathleen E. Sullivan]

Slightly worrisome story, but don't let the umbilical cord focus you  
too much on neutrophils.  With really vigilant cleaning it can take 8  
weeks for the cord to fall off.  No bugs- no neutrophil migration.

Kate
Kathleen E. Sullivan MD PhD
Chief, Division of Allergy and Immunology
Professor of Pediatrics
The Children's Hospital of Philadelphia
(p) 215-590-1697
(f) 267-426-0363


On Mar 5, 2008, at 2:52 PM, Chris Seroogy wrote:


> Dear Colleagues:

>

> I saw an 8 week old FT male in clinic this week with a solidly  

> attached

> umbilical stump.  He has had two hospitalizations for pneumonia.   

> One at 3

> weeks (documented RSV) and the second bilateral infiltrates  

> responsive to

> antibiotics 2 weeks ago with documented resolution.  His weight is  

> at the

> 10%ile and down from birth (25-50%ile).  Normal immunoglobulins,  

> normal T, B

> and NK cell numbers.  Initially with the second hospitalization he was

> slightly neutropenic (ANC 1000) and this has normalized.  He has  

> never had a

> leukocytosis on numerous CBCs.  His flow for CD18 and CD11b is  

> normal.  I

> intend to send DHR.  It seems he needs more PMN functional studies,  

> but I am

> perplexed by the lack of leukocytosis.  I welcome any thoughts.   

> Regards,

> Chris

>

>

> Chris Seroogy, M.D.

>

> Assistant Professor

>

> Dept. of Pediatrics

>

> Mail:  H4/474 CSC, Mailstop 4108

>

> Shipping:  H4/431 CSC, Mailstop 4108

>

> 600 Highland Ave.

>

> Madison, WI  53792

>

> phone: 608- 263-2652

>

> fax: 608-265-0164

>


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