[PAGID] Use of Rituximab in opsoclonus-myoclonus syndrome

[Belohradsky, Bernd Prof. Dr.]

Annette Jansson, MD is our Rituximab expert, running a German pediatric
rituximab registry; may be she would like to comment; best regards,
Bernd H.Belohradsky
(University Childrens Hospital, Munich) (Dr.Jansson should be back in
her office on Monday, February 9th)

________________________________

Von: pagid-bounces at list.clinimmsoc.org
[mailto:pagid-bounces at list.clinimmsoc.org] Im Auftrag von Eleonora
Gambineri
Gesendet: Montag, 2. Februar 2009 10:22
An: pagid at list.clinimmsoc.org
Betreff: [PAGID] Use of Rituximab in opsoclonus-myoclonus syndrome


Dear all, 

I was asked from the neurology department of my hospital to give an
opinion regarding treatment with Rituximab in opsoclonus-myoclonus
syndrome. I have checked in the literature and there are few reports
describing a beneficial effect of Rituximab in combination with IVIG.
Although there is no clear indication on how to perform this treatment.
Usually Rituximab is given once a week for 4 weeks, sometime is given
for 4 weeks but not always IVIG are started right after and are not
given monthly as in hypo/agammaglobulinemia? When would you start IVIG?

Any thoughts or suggestions will be kindly appreciated. 

Best wishes,
Eleonora

*******************************************************************
Dott.ssa Eleonora Gambineri
Ricercatore Universitario
Universita' degli Studi di Firenze
Dipartimento di Pediatria-Ospedale Pediatrico "Anna Meyer"
Viale Gaetano Pieraccini, 24
50139 FIRENZE
Tel 055 5662405 (ufficio)
       055 5662464 (lab)
Fax 055 4221012
e-mail: eleonora.gambineri at unifi.it; e.gambineri at meyer.it

Eleonora Gambineri, MD
Researcher/Assistant Professor
University of Florence
Department of Pediatrics-"Anna Meyer" Children's Hospital
Viale Gaetano Pieraccini, 24
50139 FIRENZE
ITALY
Tel +39 055 5662405 (office)
       +39 055 5662464 (lab)
Fax +39 055 4221012
e-mail: eleonora.gambineri at unifi.it; e.gambineri at meyer.it
********************************************************************





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