[CIS-PAGID] CVID Pt wheezes 12h after Hizentra

[Church, Joseph]

Colleagues:

 

I recently started to follow a 57yo lady with CVID.  She has lots of
other complaints (fatigue, arthralgias, thyroid disease, migraines,
mitral valve prolapse...).

 

She had significant reactions following Vivaglobin: fatigue, nausea,
hives.

 

She is receiving Hizentra.  Approximately 12h after each infusion she
complains of wheezing.  This is responsive to Xopenex and not of a
severity to consider discontinuing the infusions.  

 

Has anyone seen this in patients following SCIG?  

 

IgG anti-IgA is pending.

 

Thank you for your thoughts.

 

Joe Church

Children's Hospital Los Angeles



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