[CIS PIDD] [cis-pidd] Neutropenia and low interferon gamma production

[Wiens, Lynn A MD]

Immunoglobulin levels are normal and the assay was performed at
Viracor-IBT using their T-cell FX complete panel. 

 

Lynn A. Wiens, MD

Cell: 918-550-1200

http://tulsaallergynews.com <http://tulsaallergynews.com> 

 

 

From: Church, Joseph [mailto:JChurch at chla.usc.edu] 
Sent: Thursday, September 04, 2014 09:11
To: CIS-PIDD
Subject: RE:[cis-pidd] Neutropenia and low interferon gamma production

 

What assay was done for INF-g production?

 

Were immunoglobulin levels normal?  

 

Joe Church

Children's Hospital Los Angeles

 

From: Wiens, Lynn A MD [mailto:lawiens at saintfrancis.com] 
Sent: Thursday, September 04, 2014 7:01 AM
To: CIS-PIDD
Subject: [cis-pidd] Neutropenia and low interferon gamma production

 

I am taking care of a 2 yo male with idiopathic neutropenia doing well
on Neupogen.  As part of his work-up, I obtained T-cell function and PHA
did upregulate CD 69 but there was no interferon gamma production.  In
vitro proliferation to tetanus toxoid, viral mixture, candida was low.
Response to PWM; staph superantigen was normal.  

My question is what additional genetic testing is indicated in a boy
doing well with neupogen; no additional infections since starting.  

Lynn A. Wiens, MD

Warren Clinic

6160 South Yale Avenue  Tulsa, OK 74136

Specializing in the care of Allergy, Asthma, Sinus disease, and Chronic
Infections

http://tulsaallergynews.com <http://tulsaallergynews.com> 

Office: 918-495-2636

Cell: 918-550-1200

 

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