[CIS PIDD] [cis-pidd] Training to be Veterinarian w CVID

[CIS-PIDD]

Dear Friends and Colleagues

I have a 24yo with CVID who has done well on Ab replacement (no unusual infections etc..)- normal numbers of T cells who is in Veterinary School. She is required to receive the rabies vaccine and show anti-rabies Ab post-vaccination. Not surprisingly, she had no response to the vaccine. It is my understanding that the rabies immunoglobulin provides only temporary protection in the event of a bite until the rabies vaccine elicits an antibody response.  As a veterinarian, she will be at some increased risk for rabies, depending on exactly what she decides to do. Has anyone else had a similar situation (maybe a veterinarian subsequently diagnosed with CVID)? Any advice on how to manage this difficult and unusual situation would be appreciated.
Thanks

Jack Routes

John M. Routes, MD
Chief, Section of Allergy and Clinical Immunology
Professor of Pediatrics, Medicine, Microbiology and Molecular Genetics
Department of Pediatrics
Children's Hospital of Wisconsin
Medical College of Wisconsin
9000 W. Wisconsin Ave.
Milwaukee, WI  53226-4874

Phone: 414-266-6061
Fax: 414-266-6437
Email: jroutes at mcw.edu<mailto:jroutes at mcw.edu>

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